![]() Vignoletti F, Matesanz P, Rodrigo D, Figuero E, Martin C, Sanz M (2012) Surgical protocols for ridge preservation after tooth extraction. Int J Periodontics Restorative Dent 23:313–323 Schropp L, Wenzel A, Kostopoulos L, Karring T (2003) Bone healing and soft tissue contour changes following single-tooth extraction: a clinical and radiographic 12-month prospective study. Van der Weijden F, Dell-Acqua F, Slot DE (2009) Alveolar bone dimensional changes of post-extraction sockets in humans: a systematic review. Within the limitations of this review, improvement in bone repair can be found when using photobiomodulation in extraction sockets.įarine R, Tombelli L (2012) Wound healing of extraction sockets. ![]() Higher concentration of osteogenesis markers Ocn and Runx2 were consistently reported across studies, as well as higher percentage of bony trabeculae and bone density. No side effects of photobiomodulation have been reported. Six studies measured bone density or bone trabeculae percentage, while remaining studies measured secondary outcome measures such as osteogenesis markers, patient’s self-reported pain scores, and clinical epithelial regeneration. Laser parameters applied varied between studies significantly. Test subjects included humans (3), rats (5), and rabbits (2), either healthy or with specified systemic condition(s). After applying the inclusion criteria, ten studies were selected for review. ![]() PubMed, Cochrane Library, and Scopus electronic databases were searched for in vivo studies with restrictions on the year (< 50 years old) and language (English). A search strategy was developed in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. This systematic review aims to evaluate whether photobiomodulation accelerates bone healing in those sockets. Post-extraction healing of the socket may take up to 24 weeks to complete.
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